What is Case Receipt in Pharmacovigilance?

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This blog covers the following topics:

  1. Insights into receipt dates in pharmacovigilance.
  2. Comprehensive overview of different receipt dates.
  3. The relevance of receipt dates in follow-up reports.

Table of Contents:

  1. What are receipt dates
  2. MRD/IRD in detail
  3. CRD/SRD in detail
  4. Conclusion
  5. References
  6. FAQ

Overview

This below article meant for those who may confused about a particular topic.

Yes, about the receipt dates in pharmacovigilance case processing.

Yet, if you are already familiar with the topic. In this blog you may get a chance of exploring something new about this topic.

“Break free from the shadows of misconception. In the realm of case submissions, precision is power. Embrace compliance and significance with Drugvigil – where your data transforms into impactful narratives.”

Notification: While perusing this blog, we also provide a complimentary checklist to enhance your ICSR case processing. Feel free to access it while navigating through the content.

Receipt dates

In pharmacovigilance, receipt dates are crucial for regulatory submissions at-least in case processing.

There are two important dates that are often the same or sometimes different:

  1. MRD/IRD
  2. CRD/SRD

These dates mark when cases in and out in various levels.

✍️ Note: It called by various terms based on their internal naming conventions. However, mentioning here the most commonly used terms in the field of pharmacovigilance.

MRD/IRD:

MRD/IRD stands for Manufacture/Initial Receipt Date.

It signifies the initial reception of a case, when the adverse event report first comes aware. Alternatively, it can be referred to as day zero.

📢 Recommendations: I recommend checking our existing blog where we discuss the significance of receipt dates Your text here, Hi this is test file testing block. explained the concept of day-zero in pharmacovigilance.
MRD/IRD in detail:

It’s the date when a report about a reaction or event to a specific drug submitted by a reporter or consumer.

This report is first becomes aware by the company that produce the drug.

The report either reported to:

  1. Directly to manufacturer
  2. To regulatory bodies
  3. MAH
  4. Designated department to record these reports

CRD/SRD:

CRD/SRD stands for Central/Safety Receipt Date.

This marks the date where the case received by central unit.

Here central unit signifies the safety processing unit.

This date signifies when the report received by the central unit for processing.

CRD/SRD in detail:

It is the date, once the initial report filed, i.e, what we see earlier MRD/IRD. It is then should forward to the relevant team or department (safety processing unit) for:

  1. Further Evaluation
  2. Assessment and
  3. Submission

which mostly occur on the same day or sometime may delay.

So since you are in a case processing team, the day when the report received and registered within your department considered CRD/SRD.

This process called intake of cases. It typically booked and routed to data entry on the same day, with the order of priority.

📢 If you’re wonder to explore, click here to discover the step-by-step considerations in the book-in process.

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Conclusion

Based on the above discussion, we hope that we explored something significant in deep. It is a very important factor within pharmacovigilance many not notices it.

Thumbs up if you got some clarity and we appreciate your valuable recommendations.

And also you can pin point us if we miss anything crucial.

Your comments are welcome.

References:
  1. EMA GVP Guidelines
FAQ:

What does case receipts refer to in pharmacovigilance?

Case receipts are the dates when information is received at various levels within the case processing unit.

What are the two Types of case receipts?

1. MRD/IRD stands for Manufacture Receipt Date/Initial Receipt Date
2. CRD/SRD stands for Central Receipt Date and Safety Receipt Date

These terms might vary within different conventions, but here we’re referring to the most commonly used terminology.

What is MRD/IRD?

These two terms refer to the identical dates when the case information is initially filed.

What is CRD/SRD?

These two terms refer to the same dates, indicating the information received from the initial filing stage to the safety processing team.

Disclaimer: We write this blog based on our experience and extensive knowledge, supported by references. Please note that we are not responsible for the content on the referenced websites. If you come across any misinformation or misguidance or spelling mistakes, kindly inform us promptly.



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Meet Bala, the founder of Drugvigil, a service provider specializing in pharmacovigilance. He’s not only an expert in this field, but also a passionate entrepreneur who enjoys creating new opportunities and helping others grow. Despite starting from scratch, he’s determined to develop his company from the ground up. If you’re interested in his work, be sure to show your support and share his message with others.




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Comments

4 responses to “What is Case Receipt in Pharmacovigilance?”

  1. […] It’s essential to grasp these terms for effective case management. I encourage you to visit our blog for an in-depth exploration of what case receipts entail. […]

  2. […] Recommendations: I highly recommend our two existing blogs that you may not be aware of, which cover the topics of “Receipt Dates” and “The Significance of Receipt […]

  3. […] section differ the cases by the receipt dates of each reports, which can be helpful in locating the relevant […]

  4. […] I recommend checking out two of our existing blogs that are closely related. The first covers what is case receipt in case processing, and the second explores the relationship between Day-Zero and receipt […]

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